Zoledronic Acid Actavis Storage

Store below 30°C.
Keep Zoledronic acid Actavis out of the sight and reach of children.
Shelf life after dilution: Chemical and physical in-use stability has been demonstrated for 24 hours at 2°C - 8°C and at 25°C after dilution in 100 ml 0.9% w/v sodium chloride solution or 100 ml 5% w/v glucose. From a microbiological point of view, the solution for infusion should be used immediately after dilution. If not used immediately, inuse storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2°C - 8°C. If refrigerated, the solution must be allowed to reach room temperature before administration.
The solution containing zoledronic acid is given as a single 15 minute intravenous infusion in a separate infusion line. The hydration status of patients must be assessed prior to and following administration of Zoledronic acid Actavis to ensure that they are adequately hydrated.
Since no data are available on the compatibility of Zoledronic acid Actavis with other intravenously administered substances, Zoledronic acid Actavis must not be mixed with other medications/substances and should always be given through a separate infusion line.